Understanding pathogenic processes and the development of successful strategies in combating infection requires access to comprehensive information accumulated in the literature describing pathogenic pathways and related components. Integrated with genomic data, bioinformatics tools and experimental information can facilitate scientific insight into mechanisms of pathogenesis and assist in experimental planning.

Information regarding the components of pathogenic pathways and their relationships comes from vast data sources. The accumulation and analysis of this information will allow researchers to explore genomic and experimental data in the framework of pathogenic pathways and perform reconstructions of the pathogenic pathways from the sequence data. The current lack of such a resource can hinder the ability and efficiency to analyze genomic data and build comprehensive computational models of pathogenic processes based on the experimental results.

We are developing a comprehensive database of pathogenic pathways and related components based on information extracted from the literature.

Pathways have been constructed for the following processes:
   1. Bacterial Adhesion
   2. Bacterial Capsules and Relevant Metabolic Pathways
   3. Bacterial Secretion Pathways
   4. Invasion Strategies

UNDER CONSTRUCTION