Drug ID Drug Name Synonyms Target Target Pathway Pubchem CID 1 Erlotinib Tarceva, RG-1415, CP-358774, OSI-774, Ro-508231, R-1415 EGFR EGFR signaling 176870 3 Rapamycin AY-22989, Sirolimus, WY-090217, Torisel, Rapamune MTORC1 PI3K/MTOR signaling 5384616 5 Sunitinib Sutent, Sunitinib Malate, SU-11248 PDGFR, KIT, VEGFR, FLT3, RET, CSF1R RTK signaling 5329102 6 PHA-665752 PHA665752, PHA 665752 MET RTK signaling 10461815 9 MG-132 LLL cpd, MG 132, MG132 Proteasome, CAPN1 Protein stability and degradation 462382 11 Paclitaxel BMS-181339-01, Taxol, Onxol, Paxene, Praxel, Abraxane Microtubule stabiliser Mitosis 36314 17 Cyclopamine - SMO Other several 29 AZ628 AZ-628, AZ 628 BRAF ERK MAPK signaling 11676786 30 Sorafenib Nexavar, 284461-73-0, BAY 43-9006 PDGFR, KIT, VEGFR, RAF RTK signaling 216239 32 Tozasertib MK 0457,MK-0457,MK-045, VX-680 VX 680 VX-68 AURKA, AURKB, AURKC, others Mitosis 5494449 34 Imatinib Gleevec, STI-571 ABL, KIT, PDGFR RTK signaling 5291 35 NVP-TAE684 NVP-TAE 684, TAE684, TAE-684 ALK RTK signaling 16038120 37 Crizotinib Xalkori, PF2341066, PF-2341066, PF 2341066 MET, ALK, ROS1 RTK signaling 11626560 38 Saracatinib AZD0530, AZD-0530, AZ-10353926 ABL, SRC RTK signaling 10302451 41 S-Trityl-L-cysteine NSC 83265, Tritylcysteine KIF11 Mitosis 76044 45 Z-LLNle-CHO Z-L-Norleucine-CHO, Gamma-Secretase Inhibitor 1 gamma-secretase Other 16760646 51 Dasatinib BMS-354825-03, BMS-354825, Sprycel ABL, SRC, Ephrins, PDGFR, KIT Other 3062316 52 GNF-2 KIN001-013 BCR-ABL ABL signaling 5311510 53 CGP-60474 KIN001-019, CGP60474, CGP 60474 CDK1,CDK2,CDK5,CDK7,CDK9, PKC Cell cycle 644215 54 CGP-082996 CINK4, KIN001-021 CDK4 Cell cycle 24825971 55 A-770041 KIN001-111 LCK, FYN Other, kinases 9549184 56 WH-4-023 KIN001-112 SRC, LCK Other, kinases 11844351 59 WZ-1-84 KIN001-123 BMX Other, kinases 49821040 60 BI-2536 - PLK1, PLK2, PLK3 Cell cycle 11364421 62 BMS-536924 BMS 536924 IGF1R, IR IGFR signaling 10390396 63 BMS-509744 KIN001-127, ITK inhibitor ITK Other 20635522 64 CMK KIN001-128 RSK2 ERK MAPK signaling 16663089 71 Pyrimethamine Daraprim, Chloridine Dihydrofolate reductase (DHFR) Other 4993 83 JW-7-52-1 NA MTOR PI3K/MTOR signaling 49836027 86 A-443654 KIN001-139 AKT1, AKT2, AKT3 PI3K/MTOR signaling 10172943 87 GW843682X GW843682X (AN-13) PLK1 Cell cycle 9826308 88 Entinostat MS-275 HDAC1, HDAC3 Chromatin histone acetylation 4261 89 Parthenolide - HDAC1 Chromatin histone acetylation 7251185 91 GSK319347A KIN001-135, IKK-3 inhibitor IKK Other 11626927 94 TGX221 TGX-221, Tgx 221 PI3Kbeta PI3K/MTOR signaling 9907093 104 Bortezomib PS-341, LDP-341, Velcade Proteasome Protein stability and degradation 387447 106 XMD8-85 ERK5-IN-1 ERK5, BET Other 46844147 110 Seliciclib Roscovitine, CYC-202, AL-39256 CDK2, CDK7, CDK9 Cell cycle 160355 111 Salubrinal EIF-2alpha Inhibitor EIF2A Other 5717801 119 Lapatinib Tykerb, Tyverb ERBB2, EGFR EGFR signaling 208908 127 GSK269962A GSK 269962A ROCK1, ROCK2 Cytoskeleton 16095342 133 Doxorubicin Doxil, Rubex, Adriamycin, Adriablastin, Doxorubicine Anthracycline DNA replication 31703 134 Etoposide Etopophos, Vepesid, Eposin, VP-16 TOP2 DNA replication 36462 135 Gemcitabine Gemzar, LY-188011 Pyrimidine antimetabolite DNA replication 60750 136 Mitomycin-C Mytozytrex, NSC-26980, MMC, Mitosol, Mitozytrex DNA crosslinker DNA replication 5746 140 Vinorelbine vinorelbine tartrate, Navelbine, Exelbine Microtubule destabiliser Mitosis - 147 NSC-87877 NSC 87877 SHP-1 (PTPN6), SHP-2 (PTPN11) Other 5459322 150 Bicalutamide ICI-176334, Casodex, Cosudex, ICI 176334 AR Hormone-related 2375 151 QS11 944328-88-5 ARFGAP1 Other 4263900 152 CP466722 CP-466722, CP 466722, 1080622-86-1 ATM Genome integrity 44551660 153 Midostaurin PKC412, benzoylstaurosporine, CGP-41251 PKC, PPK, FLT1, c-FGR, others Other several 154 CHIR-99021 CT 99021, CHIR99021, CHIR 99021 GSK3A, GSK3B WNT signaling 9956119 155 Ponatinib AP24534, AP-24534, KIN001-192, Iclusig ABL, PDGFRA, VEGFR2, FGFR1, SRC, TIE2, FLT3 RTK signaling 24826799 156 AZD6482 AZD 6482, AZD-6482, AK-55409 PI3Kbeta PI3K/MTOR signaling 44137675 157 JNK-9L KIN001-204, JNK inhibitor 9l JNK2, JNK3 JNK and p38 signaling 25222038 158 PF-562271 PF-00562271 FAK, FAK2 Cytoskeleton 11713159 159 HG6-64-1 KIN001-206 BRAF ERK MAPK signaling 53302361 163 JQ1 JQ-1, (+)-JQ-1 BRD2, BRD3, BRD4, BRDT Chromatin other 46907787 164 JQ12 - HDAC1, HDAC2 Chromatin histone acetylation none 165 DMOG Dimethyloxalylglcine HIF-PH Metabolism 560326 166 FTI-277 - Farnesyl-transferase (FNTA) Other 3005532 167 OSU-03012 AR-12, OSU 03012, OSU03012, PDK1 inhibitor AR-12 PDK1 (PDPK1) Other, kinases 10027278 170 Shikonin Anchusin not defined Other 5208 171 AKT inhibitor VIII Akti-1/2 AKT1, AKT2, AKT3 PI3K/MTOR signaling 10196499 172 Embelin Emberine, Embelic acid XIAP Apoptosis regulation 3218 173 FH535 - PPARgamma, PPARdelta WNT signaling 3463933 175 PAC-1 GTPL5238 Procaspase-3, Procaspase-7 Apoptosis regulation 6753378 176 IPA-3 IPA 3 PAK1 Cytoskeleton 521106 177 GSK650394 GSK-650394, GSK 650394 SGK2, SGK3 Other 25022668 178 BAY-61-3606 Syk Inhibitor, BAY-613606 SYK Other, kinases 10200390 179 5-Fluorouracil 5-FU Antimetabolite (DNA & RNA) Other 3385 180 Thapsigargin Octanoic acid SERCA Other 446378 182 Obatoclax Mesylate GX15-070MS, Obatoclax, GX15-070 BCL2, BCL-XL, BCL-W, MCL1 Apoptosis regulation 11404337 184 BMS-754807 BMS754807, BMS 754807 IGF1R, IR IGFR signaling 24785538 185 Linsitinib OSI-906, ASP-7487 IGF1R IGFR signaling 11640390 186 Bexarotene LG-100069, Targretin, Targret, Targrexin, Targretyn, Bexarotenum Retinioic X receptor (RXR) agonist Other 82146 190 Bleomycin - dsDNA break induction DNA replication several 192 LFM-A13 DDE-28 BTK Other, kinases 54676905 193 GW-2580 GX2580, CFMS receptor tyrosine kinase inhibitor CSF1R RTK signaling 11617559 194 Luminespib AUY922, VER-52296,NVP-AUY922, AUY HSP90 Protein stability and degradation 10096043 196 Phenformin DBI Biguanide agent Other 8249 197 Bryostatin 1 Bryostatin PKC Other, kinases 5280757 199 Pazopanib Votrient CSF1R, KIT, PDGFRA, PDGFRB RTK signaling 10113978 200 Dacinostat NVP-LAQ824, LAQ824 HDAC1 Chromatin histone acetylation 6445533 201 Epothilone B Patupilone, EpoB, EPO906, GNF-PF-193 Microtubule stabiliser Mitosis 448013 202 GSK1904529A GSK-1904529A, GSK 1904529A IGF1R, IR IGFR signaling 25124816 203 BMS-345541 BMS345541, IKK Inhibitor 3 IKK1, IKK2 Other, kinases 9813758 204 Tipifarnib Zarnestra Farnesyl-transferase (FNTA) Other 159324 205 Avagacestat BMS-708163, BMS 708163 Amyloid beta20, Amyloid beta40 Other 46883536 206 Ruxolitinib INCB-18424, Ruxolitinib Phosphate, Jakafi JAK1, JAK2 Other, kinases 25126798 207 AS601245 - JNK1, JNK2, JNK2 JNK and p38 signaling 10109823 208 Ispinesib Mesylate SB-715992 KSP Mitosis 6450816 211 TL-2-105 - not defined ERK MAPK signaling none 219 AT-7519 AT7519 CDK1, CDK2, CDK4, CDK6, CDK9 Cell cycle 11338033 221 TAK-715 KIN001-201, TAK 715 p38alpha, p38beta JNK and p38 signaling 9952773 222 BX-912 - PDK1 (PDPK1) PI3K/MTOR signaling 11754511 223 ZSTK474 KIN001-167, ZSTK-474, ZSTK 474 PI3K (class 1) PI3K/MTOR signaling 11647372 224 AS605240 KIN001-173, AS-605240 PI3Kgamma PI3K/MTOR signaling 5289247 225 Genentech Cpd 10 - AURKA, AURKB Mitosis none 226 GSK1070916 GSK-1070916 AURKA, AURKC Mitosis 46885626 228 AKT inhibitor VIII Akti-1/2, KIN001-102 AKT1, AKT2, AKT3 PI3K/MTOR signaling 10196499 229 Enzastaurin LY317615 PKCB Other, kinases 176167 230 GSK429286A - ROCK1, ROCK2 Cytoskeleton 11373846 231 FMK KIN001-242 RSK Other, kinases none 235 QL-XII-47 - BTK, BMX Other, kinases none 238 Idelalisib CAL-101, Zydelig PI3Kdelta PI3K/MTOR signaling 11625818 245 UNC0638 UNC-0638, UNC 0683 G9a and GLP methyltransferases Chromatin histone methylation 46224516 249 Cabozantinib BMS-907351, XL-184, Cometriq VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, TIE2,AXL Other, kinases 25102847 252 WZ3105 - SRC, ROCK2, NTRK2, FLT3, IRAK1, others Other none 253 XMD14-99 - ALK, CDK7, LTK, others Other none 254 Quizartinib AC220, AC 220, AC-220, Asp-2689 FLT3 RTK signaling 24889392 255 CP724714 CP-724714 ERBB2 EGFR signaling 9874913 256 JW-7-24-1 - LCK Other, kinases none 257 NPK76-II-72-1 - PLK3 Cell cycle none 258 STF-62247 STF62247 Autophagy inducer Other 704473 260 NG-25 NG25 TAK1, MAP4K2 Other, kinases 53340664 261 TL-1-85 - TAK Other, kinases none 262 VX-11e VX11e, VX11e ERK2 ERK MAPK signaling 11634725 263 FR-180204 FR 180204, FR180204, ERK Inhibitor II ERK1, ERK2 ERK MAPK signaling 11493598 265 Tubastatin A - HDAC1, HDAC6, HDAC8 Chromatin histone acetylation 53394750 266 Zibotentan ZD4054, ZD-4054 Endothelin-1 receptor (EDNRA) Other 9910224 268 Sepantronium bromide YM155, YM-155, YM 155 BIRC5 Apoptosis regulation 11178236 269 NSC-207895 XI-006, NSC207895 MDM4 p53 pathway 42640 271 VNLG/124 HDAC inhibitor XV HDAC,RAR Chromatin histone acetylation 24894414 272 AR-42 HDAC-42, AR 42, AR42 HDAC1 Chromatin histone acetylation 6918848 273 CUDC-101 CUDC 101 HDAC1-10, EGFR, ERBB2 Other 24756910 274 Belinostat PXD101, PXD-101 HDAC1 Chromatin histone acetylation 6918638 275 I-BET-762 GSK525762A BRD2, BRD3, BRD4 Chromatin other 46943432 276 CAY10603 - HDAC1, HDAC6 Chromatin histone acetylation 24951314 277 Linifanib ABT-869, ABT 869 VEGFR1, VEGFR2, VEGFR3, CSF1R, FLT3, KIT RTK signaling 11485656 279 BIX02189 BIX 02189 MEK5, ERK5 ERK MAPK signaling 46931012 281 Alectinib CH5424802, CH 542802, Alecensa ALK RTK signaling 49806720 282 Pelitinib EKB-569, EKB 569 EGFR EGFR signaling 6445562 283 Omipalisib GSK2126458, GSK-2126458, EX-8678, GSK458 PI3K (class 1), MTORC1, MTORC2 PI3K/MTOR signaling 25167777 286 KIN001-236 - Angiopoietin-1 receptor Other none 287 KIN001-244 PDK1 inhibitor 7 PDK1 (PDPK1) Other, kinases 56965967 288 WHI-P97 AC1L1GQE, KIN001-055 JAK3 Other, kinases 3796 290 KIN001-260 Bayer IKKb inhibitor, ACHP IKKB Other 10451420 291 KIN001-266 - MAP3K8 Other, kinases 44143370 292 Masitinib AB1010, Masivet KIT, PDGFRA, PDGFRB Other, kinases 10074640 293 Amuvatinib MP470, MP 470, MP-470 KIT, PDGFRA, FLT3 Other, kinases 11282283 294 MPS-1-IN-1 - MPS1 Mitosis 25195352 295 NVP-BHG712 BHG712 EPHB4 Other 16747388 298 OSI-930 OSI 930 OSI930 KIT RTK signaling 9868037 299 OSI-027 A-1065-5 MTORC1, MTORC2 PI3K/MTOR signaling 44224160 300 CX-5461 CX5461, CX 5461 RNA Polymerase 1 Other 25257557 301 PHA-793887 PHA793887, PHA 793887 CDK2, CDK7, CDK5 Cell cycle 46191454 302 PI-103 PI-103, PI103, PI 103 PI3Kalpha, DAPK3, CLK4, PIM3, HIPK2 PI3K/MTOR signaling 9884685 303 PIK-93 PIK 93, PIK93 PI3Kgamma PI3K/MTOR signaling 6852167 304 SB52334 SB-52334, SB 52334 ALK5 RTK signaling 9967941 305 TPCA-1 - IKK2 Other, kinases 9903786 306 Fedratinib TG101348, TG-101348, SAR302503, SAR-302503 JAK2 Other, kinases 16722836 308 WIKI4 WIKI-4, WIKI 4 TNKS1, TNKS2 WNT signaling 2984337 309 Y-39983 - ROCK Cytoskeleton 9810884 310 YM201636 YM-201636, YM 201636 PYKFYVE Other 9956222 312 Tivozanib AV-951, AV 951, KRN-951, KIL8951, ASP-4130 VEGFR1, VEGFR2, VEGFR3 RTK signaling 9911830 326 GSK690693 GSK 690693, GSK-690693 AKT1, AKT2, AKT3 PI3K/MTOR signaling 16725726 328 SNX-2112 SNX 2112 HSP90 Protein stability and degradation 24772860 329 QL-XI-92 - DDR1 Other none 330 XMD13-2 - RIPK1 Apoptosis regulation none 331 QL-X-138 - BTK Other, kinases none 332 XMD15-27 - CAMK2 Other, kinases none 333 T0901317 TO-901317, TO901317 LXR, FXR Other 447912 341 Selisistat EX-527, EX 527 SIRT1 Chromatin histone acetylation 5113032 344 THZ-2-49 - CDK9 Cell cycle none 345 KIN001-270 CDK9 inhibitor, CDK9-IN-1 CDK9 Cell cycle 66577006 346 THZ-2-102-1 - CDK7 Cell cycle none 1001 AICA Ribonucleotide AICAR, N1-(b-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide AMPK agonist Metabolism 65110 1003 Camptothecin 7-Ethyl-10-Hydroxy-Camptothecin, SN-38, Irinotecan, Camptothecin-11, Camptosar TOP1 DNA replication 104842 1004 Vinblastine Velban Microtubule destabiliser Mitosis 6710780 1005 Cisplatin cis-Diammineplatinum(II) dichloride, Platinol, CIS-DDP DNA crosslinker DNA replication 84691 1006 Cytarabine Ara-Cytidine, Arabinosyl Cytosine, U-19920 Antimetabolite DNA replication 6253 1007 Docetaxel RP-56976, Taxotere Microtubule stabiliser Mitosis 148124 1008 Methotrexate Abitrexate, Amethopterin, Rheumatrex, Trexall, Folex Antimetabolite DNA replication 126941 1009 Tretinoin ATRA, Vesanoid, Renova, Atralin, Tretin-X, Avita Retinoic acid Other 444795 1010 Gefitinib ZD-1839, Iressa EGFR EGFR signaling 123631 1011 Navitoclax ABT-263, ABT263, ABT 263 BCL2, BCL-XL, BCL-W Apoptosis regulation 24978538 1012 Vorinostat Zolinza, SAHA, suberanilohydroxamic acid, suberoylanilide hydroxamic acid, MK-0683 HDAC inhibitor Class I, IIa, IIb, IV Chromatin histone acetylation 5311 1013 Nilotinib Tasigna, AMN 107 ABL ABL signaling 644241 1014 Refametinib RDEA119, BAY-86-9766, BAY 869766 MEK1, MEK2 ERK MAPK signaling 44182295 1015 CI-1040 CI 1040, PD-18435, PD-184352, 212631-79-3 MEK1, MEK2 ERK MAPK signaling 6918454 1016 Temsirolimus CCI-779, Torisel MTOR PI3K/MTOR signaling 6918289 1017 Olaparib AZD2281, KU0059436, Lynparza PARP1, PARP2 Genome integrity 23725625 1018 Veliparib ABT-888, ABT888, ABT 888 PARP1, PARP2 Genome integrity 11960529 1019 Bosutinib SKI-606, Bosulif SRC, ABL, TEC Other, kinases 5328940 1020 Lenalidomide CDC-501, CC-5013, Revlimid CRBN Protein stability and degradation 216326 1021 Axitinib AG-13736, Inlyta PDGFR, KIT, VEGFR RTK signaling 6450551 1022 AZD7762 AZD-7762, AZD 7762 CHEK1, CHEK2 Cell cycle 11152667 1023 GW441756 GW 441756 NTRK1 RTK signaling 9943465 1024 Lestauritinib CEP-701, SP-924, SPM-924, A-154475, KT-555 FLT3, JAK2, NTRK1, NTRK2, NTRK3 Other, kinases 126565 1025 SB216763 SB-216763, SB 216763 GSK3A, GSK3B WNT signaling 176158 1026 Tanespimycin 17-AAG, BMS-722782 HSP90 Protein stability and degradation 6505803 1028 VX-702 VX702, VX 702 p38 JNK and p38 signaling 10341154 1029 Motesanib AMG-706, AMG 706, AMG706 VEGFR, RET, KIT, PDGFR RTK signaling 11667893 1030 KU-55933 KU55933 ATM Genome integrity 5278396 1031 Elesclomol STA-4783 HSP90 Protein stability and degradation 300471 1032 Afatinib BIBW2992, Tovok, Gilotrif ERBB2, EGFR EGFR signaling 10184653 1033 Vismodegib GDC0449, Erivedge SMO Other 24776445 1036 PLX-4720 PLX4720, PLX 4720 BRAF ERK MAPK signaling 24180719 1037 BX796 BX-796 TBK1, PDK1 (PDPK1), IKK, AURKB, AURKC Other 10077147 1038 NU7441 KU-57788, NU-7432, NU-7741 DNAPK Genome integrity 11327430 1039 SL0101 SL-0101, SL 0101-1 RSK, AURKB, PIM1, PIM3 Other 10459196 1042 Doramapimod BIRB-796, BIRB 796 p38, JNK2 JNK and p38 signaling 156422 1043 JNK Inhibitor VIII - JNK JNK and p38 signaling 11624601 1046 681640 - WEE1, CHEK1 Cell cycle 10384072 1047 Nutlin-3a (-) - MDM2 p53 pathway 11433190 1049 PD173074 PD-173074, PD 173074 FGFR1, FGFR3 RTK signaling 1401 1050 ZM447439 ZM-447439, ZM 447439 AURKA, AURKB Mitosis 9914412 1052 RO-3306 - CDK1 Cell cycle 44450571 1053 MK-2206 MK 2206, MK2206 AKT1, AKT2 PI3K/MTOR signaling 46930998 1054 Palbociclib PD0332991, PD-0332991, PF-00080665-73 CDK4, CDK6 Cell cycle 5330286 1057 Dactolisib NVP-BEZ235, BEZ235 PI3K (Class 1), MTORC1, MTORC2 PI3K/MTOR signaling 11977753 1058 Pictilisib GDC-0941, GDC0941, RG-7621 PI3K (class 1) PI3K/MTOR signaling 17755052 1059 AZD8055 AZD-8055 MTORC1, MTORC2 PI3K/MTOR signaling 25262965 1060 PD0325901 PD-0325901, PD 0325901 MEK1, MEK2 ERK MAPK signaling 9826528 1061 SB590885 SB-590885 BRAF ERK MAPK signaling 11316960 1062 Selumetinib AZD6244, AZD-6244, ARRY-886 MEK1, MEK2 ERK MAPK signaling 10127622 1066 AZD6482 AZD 6482, AZD-6482, AK-55409 PI3Kbeta PI3K/MTOR signaling 44137675 1067 CCT007093 - PPM1D Other 2314623 1069 EHT-1864 EHT 1864 RAC1, RAC2, RAC3 Cytoskeleton 9938202 1072 Avagacestat BMS-708163, BMS 708163 Amyloid beta20, Amyloid beta40 Other 46883536 1091 BMS-536924 BMS 536924 IGF1R, IR IGFR signaling 10390396 1114 Cetuximab Erbitux, IMC-C225, C225, IMC-225, L01XC06 EGFR EGFR signaling 85668777 1129 PF-4708671 PF 4708671, PF4708671 S6K1 PI3K/MTOR signaling 51371303 1133 Serdemetan JNJ-26854165 MDM2 p53 pathway 11609586 1142 HG-5-113-01 - LOK, LTK, TRCB, ABL(T315I) Other none 1143 HG-5-88-01 - EGFR, ADCK4 Other, kinases none 1149 TW 37 TW37, TW-37 BCL2, BCL-XL, MCL1 Apoptosis regulation 11455910 1158 XMD11-85h - BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1 Other none 1161 ZG-10 - JNK1 JNK and p38 signaling none 1164 XMD8-92 XMD 8-92 MAPK7 Other, kinases 46843772 1166 QL-VIII-58 - MTOR, ATR Other none 1170 CCT-018159 CCT018159, CCT 018159 HSP90 Protein stability and degradation 5327091 1175 Rucaparib PF-01367338, AG-014699, AG-14447, AG-14699 PARP1, PARP2 Genome integrity 9931953 1192 GSK269962A GSK 269962A ROCK1, ROCK2 Cytoskeleton 16095342 1194 SB-505124 SB 505124, SB505124 ALK4, ALK5 RTK signaling 9858940 1199 Tamoxifen Nolvadex, Soltamox, Zynoplex, ICI-46474, Kessar ESR1 Hormone-related 2733526 1203 QL-XII-61 - BMX, BTK Other, kinases none 1218 JQ1 JQ-1, (+)-JQ-1 BRD2, BRD3, BRD4, BRDT Chromatin other 46907787 1219 PFI-1 - BRD4 Chromatin other 71271629 1230 IOX2 IOX-2, IOX 2, AK176060 EGLN1 Other 54685215 1236 UNC0638 UNC-0638, UNC 0683 G9a and GLP methyltransferases Chromatin histone methylation 46224516 1239 YK-4-279 YK 4-279 RNA helicase A Other 44632017 1241 CHIR-99021 CT 99021, CHIR99021, CHIR 99021 GSK3A, GSK3B WNT signaling 9956119 1242 (5Z)-7-Oxozeaenol 5Z-7-Oxozeaenol, LL-Z1640-2 TAK1 Other, kinases 9863776 1243 Piperlongumine Piplartine Induces reactive oxygen species Other 637858 1248 Daporinad APO866, FK866, FK866 NAMPT Metabolism 6914657 1259 Talazoparib BMN-673, BMN 973 PARP1, PARP2 Genome integrity 44819241 1261 rTRAIL - TRAIL receptor agonist Apoptosis regulation none 1262 UNC1215 UNC-1215 L3MBTL3 Chromatin other 57339144 1264 SGC0946 - DOT1L Chromatin histone methylation 56962337 1268 XAV939 NVP-XAV939, XAV-939, XAV 939 TNKS1, TNKS2 WNT signaling 2726824 1371 PLX-4720 PLX4720, PLX 4720 BRAF ERK MAPK signaling 24180719 1372 Trametinib GSK1120212, Mekinist MEK1, MEK2 ERK MAPK signaling 11707110 1373 Dabrafenib GSK2118436, Tafinlar BRAF ERK MAPK signaling 44462760 1375 Temozolomide Temodar, Temodal, M-39831, SCH 52365 DNA alkylating agent DNA replication 5394 1377 Afatinib BIBW2992, Tovok, Gilotrif ERBB2, EGFR EGFR signaling 10184653 1378 Bleomycin (50 uM) - dsDNA break induction DNA replication several 1494 SN-38 7-Ethyl-10-Hydroxy-Camptothecin, Irinotecan, Camptosar TOP1 DNA replication 104842 1495 Olaparib AZD2281, KU0059436, Lynparza PARP1, PARP2 Genome integrity 23725625 1498 Selumetinib AZD6244, AZD-6244, ARRY-886 MEK1, MEK2 ERK MAPK signaling 10127622 1502 Bicalutamide ICI-176334, Casodex, Cosudex, ICI 176334 AR Hormone-related 2375 1526 Refametinib RDEA119, BAY-86-9766, BAY 869766 MEK1, MEK2 ERK MAPK signaling 44182295 1527 Pictilisib GDC-0941, GDC0941, RG-7621 PI3K (class 1) PI3K/MTOR signaling 17755052 1529 Pevonedistat MLN4924, MLN 4924, MLN-4924 NAE Other 16720766