| Understanding pathogenic processes
and the development of successful strategies in combating infection
requires access to comprehensive information accumulated in the
literature describing pathogenic pathways and related components.
Integrated with genomic data, bioinformatics tools and experimental
information can facilitate scientific insight into mechanisms of
pathogenesis and
assist in experimental planning.
Information
regarding the components of pathogenic pathways and their relationships
comes from vast data sources. The accumulation and analysis of this
information will allow researchers to explore genomic and experimental
data in the framework of pathogenic pathways and perform
reconstructions of the pathogenic pathways from the sequence data. The
current lack of such a resource can hinder the ability and efficiency
to analyze genomic data and build comprehensive computational models of
pathogenic processes based on the experimental results. We are developing a comprehensive database of pathogenic pathways and related components based on information extracted from the literature. Pathways have been
constructed for the following processes: UNDER CONSTRUCTION
|